I just finished reading (well, two days ago) Oryx and Crake by Margaret Atwood. It's a sort of cautionary tale of biotech gone wrong, about playing god, revenge, jealousy, personal pain in a complicated world, and so on. It's a really good book and there's lots to think about, the responsibility of an engineer for what they produce, for one thing.
This was only the second Atwood book I've ever read, the first being A Handmaids Tale, which was for a undergrad English class. I'll probably read a few of her others now. I tried to read Orwell's 1984 after I read The Handmaids Tale, as they deal with similar themes, but I never quite got through it, or started on it really. Too much oppressive society all at once is bad. Atwood hasn't had the pop culture impact as Orwell, but I guess he had a few years on her.